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INFORMATION ABOUT CAD TRIALS & POSSIBLE TREATMENT

CLINICAL TRIALS & Possible Treatment Options

DISCUSS ALL PROS AND CONS WITH YOUR MEDICAL PROFESSIONALS. 

 

The following list describes treatments that are among the ones most regularly reported about Cold Agglutinin Disease and by the CAD patients who visit our website. This is not intended to be a comprehensive or all-inclusive list, and it may not be appropriate for your individual situation.  It is intended simply as a guide for reference and discussion. Please be aware that all treatments, including blood transfusions, can have side effects, some known and others yet to be discovered. 


Clinical Trial Information:

ClinicalTrials.gov is a database of privately and publicly funded clinical studies conducted around the world.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the CAD Foundation.  https://coldagglutinindisease.org/clinical-trials 

  

Treatments:

Rituximab was found to be effective in treating patients with Non-Hodgkins Lymphoma, its main use, however, it is now also being used in the treatment of Cold Agglutinin Disease. Treatment options, discuss all pros and cons with your medical professionals.

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WHAT IS COLD AGGLUTININ DISEASE?

 Cold Agglutinin Disease (CAD), a rare and incurable disease, is a form of acquired autoimmune hemolytic anemia in which the body’s immune system mistakenly attacks and destroys its own red blood cells. 


 Daily living is significantly impacted by CAD since patients suffer from symptoms of low hemoglobin resulting in varying degrees of anemia. CAD can lead to blood clots, heart attack, strokes and possibly dementia. Patients always need to be vigilant about keeping warm to help reduce the likelihood of activating the cold-mediated antibodies, which cause cell death.